Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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For customer reference only.
Praziquantel is a pyrazinoquinoline compound originally developed for the treatment of schistosomiasis but has been found to have a wide spectrum of anthelminthic activity. Praziquantel is a racemate but the R (+) enantiomer is solely responsible for its antiparasitic activity. It is active against trematodes (all Schistosoma species pathogenic to man, Paragonimus westermani, and Clonorchis sinensis) and cestodes (Taenia saginata, Taenia solium, Hymenolepis nana and Diphyllobothrium latum).
(1) Praziquantel has a particularly dramatic effect on patients with schistosomiasis.Studies of those
treated have shown that within six months of receiving a dose of praziquantel,up to 90% of the damage
done to internal organs due to schistosomiasis infection can be reversed.
Pharmaceutical use, veterinary use.
INSPECTION ITEM | SPECIFICATIONS | ANALYSIS RESULTS | |
CHARACTERISTICS | A WHITE CRYSTALLINE POWDER OR SIMILAR | A WHITE POWDER | |
IDENTIFICATION | SHOULD CONFORM | CONFORM | |
MELTING POINT(°C) | 136.0 ~ 142.0 | 137.4 ~ 138.6 | |
LOSS ON DRIED (%) | ≤0.5 | 0.05 | |
RESIDUE ON IGNITION (%) | ≤0.1 | 0.04 | |
HEAVY METAL | ≤20ppm | ≤20ppm | |
PHOSPHATE (%) | ≤0.05 | ≤0.05 | |
RESIDUAL SOLVENTS | CH'LOROFORM: ≤60ppm | NOT DETECTED | |
AC'ETONE≤5000ppm | 555ppm | ||
RELATED COMPOUNDS (%) | A | ≤0.2 | 0.13 |
B | ≤0.2 | 0.03 | |
C | ≤0.2 | 0.01 | |
ASSAY(C19H24N2O2) | 98.5~101.0 | 99.28 | |
CONCLUSION: THE SAMPLE MEETS USP35 SPECIFICATIONS |
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