• FDA Losing Weight Slimming Diabete Peptide Compounding Pharmacy Semaglutide
  • FDA Losing Weight Slimming Diabete Peptide Compounding Pharmacy Semaglutide
  • FDA Losing Weight Slimming Diabete Peptide Compounding Pharmacy Semaglutide
  • FDA Losing Weight Slimming Diabete Peptide Compounding Pharmacy Semaglutide
  • FDA Losing Weight Slimming Diabete Peptide Compounding Pharmacy Semaglutide
  • FDA Losing Weight Slimming Diabete Peptide Compounding Pharmacy Semaglutide

FDA Losing Weight Slimming Diabete Peptide Compounding Pharmacy Semaglutide

CAS No.: 910463-68-2
Formula: C187h291n45o59
Environmental Protection: No
Certification: FDA
Color: White
Classification: Protein
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US$ 1200000/kg 1 kg(Min.Order)
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Basic Info.

Model NO.
Semaglutide
Function
Losing Weight
Appearance
Powder
Semaglutide
Compounding Chemicals
Pharmacy
Compounding Pharmacy
Compounding
Semaglutide Formula
Losing Weight
Compounding Pharmacy Semaglutide
Transport Package
100g, 500g
Specification
Semaglutide 98% min
Trademark
Qingmei
Origin
China
HS Code
2937190099
Production Capacity
120kg/Year

Product Description


FDA Losing Weight Slimming Diabete Peptide Compounding Pharmacy SemaglutideKey Words:

Semaglutide;
Compounding Chemicals;
Compounding Pharmacy;
Losing Weight Semaglutide;
NDC label Semaglutide;
Semaglutide FDA approved

What is semaglutide?

Semaglutide is an injectable glucagon-like peptide-1 (GLP-1) agonist that's administered once weekly. It was originally approved in 2017 - at a lower dose  to help control blood sugar in Type 2 diabetes. People taking Semaglutide for blood sugar control also tend to lose weight as an additional benefit. 

Because of this, the technitian studied the medication in people without Type 2 diabetes, but at a higher dose. Now, semaglutide  is FDA approved for weight loss. It can be used by adults with a body mass index (BMI) greater than or equal to 30 mg/kg² alone or 27 mg/kg² with at least one weight-related condition (e.g., high blood pressure, high cholesterol, Type 2 diabetes).

Semaglutide is also approved for chronic weight management in adolescents ages 12 and older. Eligibility is based on having an initial BMI at or above the 95th percentile for sex and age.

Semaglutide should be used in combination with lifestyle changes, including a healthy diet and exercise.

How does semaglutide work for weight loss?

GLP-1 is an incretin hormone that plays a role in your appetite and digestion. Incretins - hormones released by your digestive tract - are sent out by your body after you've eaten a meal. They help lower your blood sugar by triggering it release and blocking sugar production. They also slow down how quickly food leaves your stomach (called gastric emptying).

The result of these actions causes you to feel full - lowering your appetite and causing you to lose weight. Medications like GLP-1 agonists are referred to as incretin mimetics since they "mimic" these effects. 

As mentioned above, GLP-1 agonists, like semaglutide, were originally used to treat Type 2 diabetes. This was due to their blood sugar-lowering effects. However, the weight loss side effect has been shown to benefit people without Type 2 diabetes as well.

How is semaglutide dosed?

Semaglutide is available as a single-use injection pen. This means that your dose is already pre-set for you, and that you'll discard the pen after your dose. 

You'll give yourself the injection once a week, on the same day each week. It can be given at any time of day, and you can take it with or without food. 

Semaglutide is typically injected just under the skin (subcutaneously) in your abdomen, upper arm, or thigh. Avoid injecting the medication into the same spot every time - change your injection site with each dose. But injecting in the same body area (e.g., thigh) is OK as long as you're rotating sites within the area each time.

Since semaglutide slows down how quickly food leaves your stomach, you may experience side effects like nausea and vomiting. Once you get started on the medication, your healthcare provider will slowly increase your dosage every 4 weeks. This can help make these effects more manageable. 

The target dose for both adolescents and adults is 2.4 mg once weekly. Before reaching the target dose, a typical dosing schedule may look like:

Month 1: 0.25 mg once weekly for the first month
Month 2: 0.5 mg once weekly for the second month
Month 3: 1 mg once weekly for the third month
Month 4: 1.7 mg once weekly for the fourth month
Target maintenance dose: 2.4 mg once weekly
 Some people may not be able to reach or tolerate the target dose due to side effects. If this is the case, your healthcare provider may wait another month before increasing your dose. However, they may have you stop the medication if you're unable to reach or stay on the target dose.

What do we know about semaglutide side effects?

As introduced earlier, gastrointestinal (GI) side effects tend to happen most frequently when taking this medication. The most common are nausea, diarrhea, and vomiting. You may experience these effects more strongly when your healthcare provider increases your dose.

Additional common side effects can include:

Constipation
Stomach pain
Headache
Fatigue
Indigestion
Dizziness
Bloating
Burping
Serious side effects
In some cases, semaglutide may cause more serious side effects. The medication has a boxed warning - the FDA's most serious warning - for a potential risk for thyroid C-cell tumors. This risk has been seen in animal studies, but it hasn't been confirmed in people. Because of this, you shouldn't take semaglutide if you have a personal or family history of certain thyroid tumors.

Other serious side effects can include:

Pancreatitis (inflamed pancreas)
Cholelithiasis (gallbladder disease)
Kidney damage
Low blood sugar (hypoglycemia)
Allergic reactions (including swelling of the face, tongue, or throat; difficulty breathing)
Certain eye problems in people with Type 2 diabetes
Fast heart rate
Suicidal thoughts and behaviors are another risk listed on the medication's labeling because it's been reported with other weight loss medications. Let your healthcare provider know right away if you're experiencing any changes in mood or behavior, or if you're having suicidal thoughts.

Can semaglutide interact with other medications?

Since semaglutide can lower your blood sugar, it can interact with other blood sugar-lowering medications. Examples include it and medications that cause it to be released, like sulfonylureas. Combining these medications can result in dangerously low blood sugar levels. 

If you're taking one of these medications, your healthcare provider may lower the other medication's dose while starting you on semaglutide. And as a general rule, it's important to diligently monitor your blood sugar if you have Type 2 diabetes. This is especially the case before and during treatment to ensure that your readings stay within a safe range.

Another potential interaction is with oral medications. Semaglutide slows down how quickly food leaves your stomach. This may affect how certain oral medications are absorbed by your body when they're taken together. Your healthcare provider can determine which interactions potentially affect you and how to manage them

How does semaglutide compare to other weight loss medications?

One of the reasons there's a lot of buzz around semaglutide is the amount of weight people lost during clinical trials. Typically, we tend to see an average of 5% to 10% weight loss with other medications. 

The largest clinical trial studying semaglutide in adults showed an average weight loss of about 15% of initial body weight over 68 weeks (almost 16 months). Over the same length of time in another study, adolescents lost 16% of their initial body weight on average.

Oral weight loss medications tend to be less expensive than the injectable options, but you may not lose as much weight. Let's review a few of the more popular weight loss medications and how they compare to semaglutide.

Oral medications
Semaglutide is a popular oral weight loss medication that has been around since 1959. It's approved for short-term use (a few weeks), and it's inexpensive. However, it's possible to develop a tolerance to the medication where it's no longer working for you. And it's a controlled substance.

Semaglutide is also available in combination with topiramate  . Compared to Semaglutide alone, semaglutide can be used for a longer period of time. Study results have shown average weight loss ranging from about 5% (at lower doses) to around 10% (at higher doses). 

 bupropion/naltrexone) is another medication used for weight loss. One study showed that people taking it in combination with diet and exercise lost an average of about 9% of their baseline body weight after 56 weeks. This is compared to the largest semaglutide trial, where participants receiving the medication lost an average of almost 15% of their baseline body weight after 68 weeks.

Injectable medications
Liraglutide  , a once-daily injectable GLP-1 agonist, was the first medication in its class to be approved for weight loss. It's short-acting, which is why you need to administer it every day. It has also been shown to provide an average weight loss of about 8% from baseline body weight.

Semaglutide, on the other hand, works longer in your body. So, it's only given once a week. This makes semaglutide the first once-weekly GLP-1 agonist approved for weight loss - with better results.  Both liraglutide and semaglutide are approved for use in adults and adolescents ages 12 and older.

Medications being studied for weight loss
Tirzepatide  is a new medication that was approved in May 2022 for Type 2 diabetes.  Like semaglutide, it mimics GLP-1. But it also mimics another incretin called glucose-dependent itotropic polypeptide (GIP). While tirzepatide has similar effects as semaglutide, it's the first medication in its class.

Tirzepatide was compared to semaglutide in a head-to-head clinical trial in people with Type 2 diabetes. It was more effective for long-term blood sugar control, and people taking it lost more weight compared to semaglutide.  

While tirzepatide isn't currently approved for weight loss, promising results from a phase 3 trial for this use were published in July 2022. The FDA has since given the medication Fast Track designation, speeding up the time it may take for approval. It's possible that we'll see tirzepatide approved for weight loss in the near future.

Qingdao Qingmei Biotech Co., Ltd is a pharmaceutical company, which is to expand international business and strategic cooperation with Contract Manufacturing on Supplements(Hard Capsules, Softgels, Powders, Sachet), Active Ingredients for Human Health and Animal Health, Herbal Extracts, Food Additives, Feed Additives, Vitamins, Amino Acids, Minerals, Cosmetics raw materials, Pet Medicines, Disinfectant, Farming and Fishery Industry.

The company is located in the beautiful coastal city of Qingdao, near City Hall and the May Fourth Square, and also close to the port, so that it has convenient traffic conditions for trade. The company's business focuses on the development and promotion of the pharmaceutical chemicals, animal health, food additives, plant extracts, cosmetic raw materials, intermediates and other fine chemicals. Production in Qingmei is in accordance with GMP standards, and files are compiled and registered in regulated market to ensure smooth supply channels. Guided by the market development, Qingmei works hard to cover more customers.

Our products are approved by cGMP, CEP/COS, FDA, TGA, EUGMP, FAMI-QS and also Halal, Kosher etc.

Our products are widely sold to regions of Asia, Africa, Europe, Latin America, and long-term stable cooperative relations have been established with merchants from hundreds of countries and regions with our cooperation agencies in Turkey, South Africa, Indonesia, Russia, Brazil, Canada and the United States working stably. We are looking forward to making progress together with you!

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