Customization: | Available |
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Varieties: | Other |
Component: | Chemical Synthetic Drugs |
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Product Introduction:
PVP exists as white or yellowish powder and aquous solution. It can dissolve in water and a variety of organic solvents.It has good hygroscopicity, film-forming capability, complexing ability and physiology compatibility.
Specifications for Pharmaceutical Grade PVP:
Product | Povidone K15 | Povidone K17 | Povidone K25 | Povidone K30 | Povidone K60 | Povidone K90 | ||||||
Appearance | White or yellowish-white,hygroscopic powder or flakes | |||||||||||
Solubility | Freely soluble in water,in ethano(96%) and in methanol,very slightly soluble in acetone. | |||||||||||
Appearance of Solution | Clearly and not moren intensely coloured than reference solution B6,BY6or R6 | |||||||||||
Identifications | Meet ID Tests | |||||||||||
pH Value(5% in aqueous solution) | 3.0-5.0 | 3.0-5.0 | 3.0-5.0 | 3.0-5.0 | 4.0-7.0 | 4.0-7.0 | ||||||
Viscosity(Expressed as K Value) | 12.75-17.25 | 15.3-18.36 | 22.5-27.0 | 27.0-32.4 | 54.0-64.8 | 81.0-97.2 | ||||||
Adehydes(Expressed as Acetaldehyde) | 500 ppm max. | 500 ppm max. | 500 ppm max. | 500 ppm max. | 500 ppm max. | 500 ppm max. | ||||||
Peroxides(Expressed as H2O2) | 400ppm max. | 400 ppm max | 400 ppm max | 400 ppm max | 400 ppm max | 400 ppm max | ||||||
Formic Acid | 0.5% max. | 0.5% max. | 0.5% max. | 0.5% max. | 0.5% max. | 0.5% max. | ||||||
Hydrazine | 1ppm max. | 1ppm max. | 1ppm max. | 1ppm max. | 1ppm max. | 1ppm max. | ||||||
N-Vinylpyrrolidone(Impurity A) |
USP26 | 1000 ppm max. | 1000 ppm max. | 1000 ppm max. | 1000 ppm max. | 1000 ppm max. | 1000 ppm max. | |||||
Current USP/EP/BP | 10 ppm max. | 10 ppm max. | 10 ppm max. | 10 ppm max. | 10 ppm max. | 10 ppm max. | ||||||
2-Pyrrolidone(Impurity B) | 3.0% max. | 3.0% max. | 3.0% max. | 3.0% max. | 3.0% max. | 3.0% max. | ||||||
Heavy Metals(as Pb) | 10 ppm max. | 10 ppm max. | 10 ppm max. | 10 ppm max. | 10 ppm max. | 10 ppm max. | ||||||
Water | 5.0% max. | 5.0% max. | 5.0% max. | 5.0% max. | 5.0% max. | 5.0% max. | ||||||
Sulphated Ash | 0.1% max. | 0.1% max. | 0.1% max. | 0.1% max. | 0.1% max. | 0.1% max. | ||||||
Nitrogen Content | 11.5-12.8% | 11.5-12.8% | 11.5-12.8% | 11.5-12.8% | 11.5-12.8% | 11.5-12.8% |
Products | K Value | pH Value (5% in water) |
Residue NVP | Sulphated Ash | Water | Solid Content |
PVP K15 | 13-18 | 3.0-7.0 | 0.05% max. | 0.1% max. | 5.0% max. | 95-100% |
PVP K17 | 15-19 | 3.0-7.0 | 0.05% max. | 0.1% max. | 5.0% max. | 95-100% |
PVP K25 | 23-28 | 3.0-7.0 | 0.05% max. | 0.1% max. | 5.0% max. | 95-100% |
PVP K30 | 27-35 | 3.0-7.0 | 0.05% max. | 0.1% max. | 5.0% max. | 95-100% |
PVP K60 | 55-65 | 5.0-9.0 | 0.05% max. | 0.1% max. | 5.0% max. | 95-100% |
PVP K85 | 78-90 | 5.0-9.0 | 0.05% max. | 0.1% max. | 5.0% max. | 95-100% |
PVP K90 | 81-100 | 5.0-9.0 | 0.05% max. | 0.1% max. | 5.0% max. | 95-100% |
PVP K30L | 27-35 | 3.0-7.0 | 0.05% max. | 0.1% max. | 69-71% | 29-31% |
PVP K85L | 78-90 | 5.0-9.0 | 0.05% max. | 0.1% max. | 79-81% | 19-21% |
PVP K90L | 81-100 | 5.0-9.0 | 0.05% max. | 0.1% max. | 79-81% | 19-21% |
99% USP Bp CAS 9003-39-8 Polyvinylpyrrolidone Pvp K90
Polyvinylpyrrolidone PVP is one of the three major pharmaceutical new excipients and can be used as the co-solvent of tablets, granules, and injection, as the glidant of capsules, as the dispersant agent of liquid preparations and the colorant, as the stabilizer of enzyme and heat sensitive drug, as the co-precipitating agent of poorly soluble drugs, and as the detoxicant of ophthalmic drugs and lubricants.
TEST ITEMS | SPECIFICATIONS |
Appearance | White powder |
K Value | 88--96 |
N-vinylpyrrolidone ppm | < 10 |
Moisture % | < 5.0 |
Sulfateash % | < 0.1 |
PH value | 3-7 |
Nitrogen % | 11.5-12.8 |
Aldehyde % | < 0.05 |
Heavy metal (as lead) ppm | < 10 |
Hydrazine ppm | < 1.0 |
Peroxide ppm | < 400 |
Analysis room and laboratory
mode of transportation | ||
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